Unasur has already proven it is useful in South America. This unlike the UN, which is made useless in part because of the UNSC's permanent members. For example, if the US didn't keep vetoing any and all resolutions critical of Israel, sanctions regarding settlement building would have passed long ago -- and Israelis and Palestinians would be more willing to return to the negotiating table.
As for Colombia, it doesn't speak for all of South America just as Poland doesn't speak for all of the EU's. Colombia has a very different take on the Palestinian issue - one that is different from that of every other South American nation and that mirrors mainly a desire not to undo its strong ties with the US. The same way, Europe will take different paths concerning Palestine. Germany and Greece are prepared to vote against Palestinian statehood bid, whilst Ireland, Spain, Portugal, and possibly France and Belgium will vote in favour of it.
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